Status: 
Available
Level: 
PhD Project
Level: 
Masters Project
Level: 
Honours Project
Supervisor(s): 
Dr. Dietmar Oelz, Dr. Zoltan Neufeld

This project is in collaboration with the experimental group of A. Yap (UQ). We are interested in understanding how the signaling cascade starting from cortical Anillin and Rho proteins affects cortical contractility in eptihelial cell monolayers. To this end we want to simulate a "pseudo-vertex-model" based on a 2D particle description and Delauney triangulation. Our goal is to compare model predictions to experimental data on persistence and directionality of cell movement within the epithelial layer.

An additional topic is this project could also be the derivation and mathematical/numerical analysis of a continuum model for the concentration of epithelial cells.