Dr Pavlina Naydenova

Postdoctoral Research Fellow

School of Mathematics and Physics

p.naydenova@uq.edu.au

Researcher biography

Dr. Pavlina Naydenova is a National Intelligence Postdoctoral Grant Research Fellow at the University of Queensland and an affiliate of the Australian Research Council Centre of Excellence in Quantum Biotechnology. She investigates protein dynamics at the single molecule level using biomolecular optomechanics. Her research interests lie in the application of quantum tools to understand the behavior of single proteins and their dynamics on an individual level as well as the interactions between proteins in biomolecular condensates.

Dr Sasheva earned her PhD in pharmacognosy and phytochemistry from the Medical University of Sofia, Bulgaria, where she was recognized for her research on plant-derived small molecules for chemotherapy.

Publications

Book Chapters (2)

Journal Articles (9)

Book Chapters

Sasheva, Pavlina and Ionkova, Iliana (2017). Small cells for big ideas: the cytotoxic podophyllotoxin and the long journey in discovering its biosynthetic pathway. Biotechnology and production of anti-cancer compounds. (pp. 177-199) edited by Sonia Malik. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-53880-8_8

Sasheva, Pavlina and Grossniklaus, Ueli (2017). Differentially methylated region-representational difference analysis (DMR-RDA): A powerful method to identify DMRs in uncharacterized genomes. Plant epigenetics methods and protocols. (pp. 113-125) edited by Igor Kovalchuk. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4899-7708-3_10

Journal Articles

Atanasova, M. D., Sasheva, P., Yonkova, I. M. and Doytchinova, I. A. (2019). Modelling the interaction and prediction of mictrotubule assembly inhibition of podophyllotoxin and its derivatives by molecular docking. Bulgarian Chemical Communications, 51 (4), 513-520. doi: 10.34049/bcc.51.4.4987

Sasheva, Pavlina and Ionkova, Iliana (2015). Podophyllotoxin production by cell cultures of Linum thracicum ssp. Thracicum degen elicited with methyl jasmonate and salicylic acid. Comptes Rendus de L'Academie Bulgare des Sciences, 68 (7), 883-888.

Sasheva, Pavlina, Ionkova, Iliana and Stoilova, Nadezhda (2015). Methyl jasmonate induces enhanced podophyllotoxin production in cell cultures of thracian flax (linum thracicum ssp. thracicum). Natural Product Communications, 10 (7), 1225-1228. doi: 10.1177/1934578x1501000722

Ilieva, Y., Zhelezova, I., Atanasova, T., Zaharieva, M. M., Sasheva, P., Ionkova, I. and Konstantinov, S. (2014). Cytotoxic effect of the biotechnologically-derived justicidin B on human lymphoma cells. Biotechnology Letters, 36 (11), 2177-2183. doi: 10.1007/s10529-014-1612-4

Sasheva, P., Yordanova, R., Janda, T., Szalai, G. and Maslenkova, L. (2013). Study of primary photosynthetic reactions in winter wheat cultivars after cold hardening and freezing. effect of salicylic acid. Bulgarian Journal of Agricultural Science, 19 (SUPPL. 2), 45-48.

Sasheva, Pavlina, Letkarska, Gergana and Ionkova, Iliana (2013). Biotechnological production of podophyllotoxin and podophyllotoxinrelated lignans in cultures of Linum thracicum degen. Comptes Rendus de L'Academie Bulgare des Sciences, 66 (10), 1445-1450.

Ionkov, Todor, Sasheva, Pavlina, Ionkova, Iliana, Bucar, Franz and Milanova, Desislava (2013). Combined control of the bioprocess for production of C-glycosylflavones from Linum Thracicum in bioreactor. Comptes Rendus de L'Academie Bulgare des Sciences, 66 (1), 139-146.

Ionkov, Todor, Ionkova, Iliana, Momekov, Georgi and Sasheva, Pavlina (2012). Improvement bioreactor production of cytotoxic saponins in Astragalus membranaceus by combined control of the bioprocess. Comptes Rendus de L'Academie Bulgare des Sciences, 65 (10), 1447-1454.

Sasheva, Pavlina, Szalai, Gabriella, Janda, Tibor and Popova, Losanka (2010). Study of the behaviour of antioxidant enzymes in the response to hardening and freezing stress in two wheat (triticum aestivum l.) varieties. Comptes Rendus de L'Academie Bulgare des Sciences, 63 (12), 1733-1740.