Each year, around 200 million people are infected with the malaria parasite, Plasmodium falciparum, and nearly 500,000 die as a result, mostly young children. Mathematical modelling has been a key tool in the study of and intervention against malaria for more than 100 years. Such models have helped to understand transmission dynamics and to predict the impact of control programs. Although models have provided valuable insight, an incomplete description of the complexities of the biology and transmission of malaria remains as a significant hurdle to fully understand both the within-host and between-host dynamics and their impact on malaria elimination. In this talk, three areas of current research will be discussed: (i) a delay difference equation model of antigenic variation in the blood stage and its effect on length of infection; (ii) a Markov chain model of the formation of genetically novel parasites in the mosquito and how it effects parasite diversity; and (iii) a difference equation model of heterogeneity in the mosquito life cycle and the impact on malaria transmission dynamics. To address these topics, a range of mathematical models will be introduced including both within-host and between-host scales.


About Maths Colloquium

The Mathematics Colloquium is directed at students and academics working in the fields of pure and applied mathematics, and statistics. 

We aim to present expository lectures that appeal to our wide audience.

Information for speakers

Information for speakers

Maths colloquia are usually held on Mondays, from 2pm to 3pm, in various locations at St Lucia.

Presentations are 50 minutes, plus five minutes for questions and discussion.

Available facilities include:

  • computer 
  • data projector
  • chalkboard or whiteboard

To avoid technical difficulties on the day, please contact us in advance of your presentation to discuss your requirements.

Venue

Building 47A (Sir James Foote),
Room: 
141

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