A hyperbolic curvature flow for biological tissue growth
Most biological tissues are sensory, dynamic materials. They undergo
changes in their geometry and in their material properties during growth
and remodelling processes. In this talk, I will focus on a recent
mathematical model of curvature-controlled tissue growth based on a
spatio-temporal cell population model. In this model, geometry modulates
cells collectively through the evolving space available to the population
of cells. The influence of curvature on the collective crowding or
spreading of cells growing new tissue leads to a type of hyperbolic
curvature flow (with curvature-dependent normal acceleration) for the
evolution of the tissue interface. Depending on the strength of lateral
diffusion, the model exhibits complex growth patterns such as undulating
motion, efficient smoothing of irregularities, and the generation of
cusps. While some of these growth patterns can be understood analytically,
such as the shock structure in the zero-diffusion and infinite-diffusion
limits, the transition between undulating motion and efficient smoothing
that occurs at intermediate diffusion remains an open problem.
* Bio
Pascal is a lecturer in Mathematical Biology at Queensland University of
Technology (QUT), Brisbane, Australia. He has been an Australian Research
Council Early Career Research Award (ARC DECRA) Fellow (2013-2017), and
previously held appointments at Monash University (School of Mathematical
Sciences) and at the University of Western Australia (Engineering
Computational Biology Group). He holds a PhD in Theoretical Physics
(Statistical Mechanics) from the Swiss Federal Institute of Technology
Lausanne (EPFL) and a MSc in Physics from the Swiss Federal Institute of
Technology Zurich (ETHZ).
His research interests include mathematical biology, mechanobiology,
complex systems, and stochastic processes.
About Applied and computational maths seminars
Our seminars bring together UQ's applied and computational mathematics communities.
UQ and invited scientists deliver the presentations, which are informal and promote discussion.
We welcome suggestions for speakers and topics from staff, students and visitors, and encourage students to share their work.
Our seminars are usually held on Thursdays from 3pm to 4pm.
To suggest a topic or speaker, and for more information, contact Dr Dietmar Oelz or Dr Cecilia Gonzalez Tokman.